Harvard breakthrough shows stem cells can be genetically edited in the body (3 minute read)
Scientists at Harvard have successfully demonstrated that the DNA in stem cells can be edited while still in the body. Current procedures to edit stem cells required the cells to be removed from the body, which causes many complications. In the study, the scientists loaded different types of adeno-associated viruses to get CRISPR gene editing systems into different types of skin, blood, and muscle stem cells. To test whether the system worked, they used a āreporterā gene, which made the edited cells glow red. Follow up research also found that the changes to these stem cells were being passed onto new stem cells down the line. This breakthrough could lead to new treatments for genetic diseases, particularly those like muscular dystrophy, which involve tissue regeneration.